Toshihiro Sakurai | Animal reproduction | Best Researcher Award
Prof Toshihiro Sakurai, Ohu University, Japan
Based on the impressive research profile of Prof. Toshihiro Sakurai, he appears to be a highly suitable candidate for the Best Researcher Award. Below is a structured overview of his qualifications, research contributions, and the significance of his work.
Publication profile
Research Contributions
Prof. Toshihiro Sakurai is an esteemed researcher in the field of veterinary reproductive science, particularly focusing on enhancing livestock fertility. His work centers on elucidating the fetomaternal relationship during early pregnancy, aiming to improve conception rates and prevent embryonic loss in livestock.
Key Research Areas
- In Vitro Model Development: Sakurai has developed an innovative in vitro model of implantation that allows for the investigation of molecular mechanisms underlying embryo implantation.
- Signaling Molecules: His research emphasizes the expression control of interferon tau, a vital signaling molecule for pregnancy recognition in ruminants.
- Epithelial-Mesenchymal Transition (EMT): He investigates the EMT of embryonic trophoblast cells, critical for placental development and successful implantation.
Publications
Prof. Sakurai has contributed to multiple high-impact publications, highlighting his findings and advancing knowledge in reproductive biotechnology:
- Tamura et al. (2009): Explored the inhibition of angiogenesis by IGFBP7.
- Nakamura et al. (2016): Investigated the induction of IFNT-stimulated genes by exosomes during the attachment period.
- Kusama et al. (2018): Demonstrated the necessity of intrauterine exosomes for bovine conceptus implantation.
- Sakurai et al. (2023): Discussed the progressive exaptation of endogenous retroviruses in placental evolution in cattle.
Impact of Research
Prof. Sakurai’s research significantly contributes to the fields of reproductive biotechnology and livestock production efficiency. His innovative approaches and findings aim to address critical challenges in animal reproduction, potentially leading to improved agricultural productivity and sustainability.
Publication top notes
Progressive Exaptation of Endogenous Retroviruses in Placental Evolution in Cattle
Expression of NFIL3 and CEBPA regulated by IFNT induced-PGE2 in bovine endometrial stromal cells during the pre-implantation period
Characterization of Serum Metabolome and Proteome Profiles Identifies SNX5 Specific for Pregnancy Failure in Holstein Heifers
Heat stress induces oxidative stress and activates the KEAP1-NFE2L2-ARE pathway in bovine endometrial epithelial cells
1,2-Dichloropropane induces γ-H2AX expression in human cholangiocytes only in the presence of macrophages
conclusion
Prof. Toshihiro Sakurai embodies the qualities of an outstanding researcher, with impactful contributions that align well with the criteria for the Best Researcher Award. His dedication to advancing reproductive science not only benefits the scientific community but also has significant implications for agricultural practices globally.