Denise Faustman | Medicine and Health Sciences | Best Researcher Award

Published on by Research Hypothesis

Dr. Denise Faustman | Medicine and Health Sciences | Best Researcher Award

Direcotr of immunobiology laboratory | washington university school of medicine | United States

Dr. Denise Faustman is a physician-scientist whose career exquisitely bridges clinical medicine, immunology, and translational research. She earned her Ph.D. in Molecular and Cellular Biology along with her M.D. in Medicine from Washington University School of Medicine, and she holds a bachelor’s degree in Zoology & Chemistry from the University of Michigan. Over her professional journey, Dr. Faustman has held roles such as Director of the Immunobiology Laboratory at Massachusetts General Hospital and Associate Professor of Medicine at Harvard Medical School, and she continues to lead efforts in immunotherapy, autoimmunity, and metabolic modulation. Her research interests center on autoimmune disease mechanisms, autoreactive T cells, the immunoregulatory role of TNF/TNFR2, use of Bacillus Calmette–Guérin (BCG) vaccine in type 1 diabetes, epigenetic modulation of immune cells, and the intersection of immunometabolism and regenerative therapies. Her technical and methodological skills span immunology assays (flow cytometry, T-cell functional assays, cytokine profiling), epigenetic and methylation analyses, transcriptomics, metabolomics, clinical trial design, and translational biomarker development. In her career she has authored 115 documents, has accrued 5,972 citations, and holds an h-index of 42, attesting to her sustained academic influence. Professionally, Dr. Faustman has led multiple NIH-funded and translational projects, engaged in global advisory committees (including in immunology, diabetes, and regulatory policy), and established collaborations across institutions in North America and Europe. She has served on scientific advisory boards, chaired expert panels, participated in FDA and NIH review committees, and mentored many early-career scientists. Her honors include recognition for contributions to autoimmune disease research, invitations as plenary or keynote speaker at international conferences, and appointments to leadership roles in professional societies and advisory bodies. In summary, Dr. Denise Faustman combines deep scientific insight, rigorous methodological skill, leadership in translational immunology, and a track record of high-impact publications to make significant contributions both to fundamental immunology and to treatments for type 1 diabetes and other autoimmune diseases. She is well positioned to continue driving innovation in immunotherapy, to mentor the next generation of biomedical scientists, and to lead large-scale international collaborative projects that translate immunological discoveries into patient benefit.

Profile: ORCID | Scopus

Featured Publications

  1. Faustman, D. L. (2001). Reversal of established autoimmune diabetes by restoration of endogenous beta cell function. Journal of Clinical Investigation.

  2. Kodama, S., Kuhtreiber, W., Fujimura, S., Dale, E. A., & Faustman, D. L. (2003). Islet regeneration during the reversal of autoimmune diabetes in NOD mice. Science.

  3. Kühtreiber, W. M., Tran, L., Kim, T., Dybala, M., Nguyen, B., Plager, S., Huang, D., Janes, S., Defusco, A., Baum, D., Zheng, H., & Faustman, D. L. (2018). Long-term reduction in hyperglycemia in advanced type 1 diabetes: the value of induced aerobic glycolysis with BCG vaccinations.

  4. Kuhtreiber, W. M., et al. (2023). BCG clinical trial programs in advanced type 1 diabetes.

  5. Faustman, D. L., Davis, M. (2013). TNF receptor 2 and disease: autoimmunity and regenerative medicine.

 

Tianhui Yuan | Medicine and Health Sciences | Best Researcher Award

Published on by Research Hypothesis

Prof. Dr. Tianhui Yuan | Medicine and Health Sciences | Best Researcher Award

Associate Director | The First Affiliated Hospital of Guangzhou University of Medicine | China

Prof. Dr. Tianhui Yuan is a distinguished physician-scientist whose educational journey culminated in the M.D. and a Ph.D. in integrated medicine and cardiovascular science (with doctoral training at a leading university), and she currently serves as Chief Physician, Doctoral Supervisor, and Associate Director of her department while also holding a Visiting Scholar appointment in the United States. Over her career, she has held progressive roles in clinical practice, laboratory research, and academic leadership in integrative Chinese and Western medicine. Her professional experience spans directing clinical care units in cardiovascular medicine, mentoring doctoral and postdoctoral researchers, coordinating international research collaborations, and representing her institution in health policy and traditional medicine networks. Her research interests lie at the interface between traditional Chinese medicine and modern cardiovascular disease therapy, particularly focusing on mechanisms and therapeutic strategies for heart failure, cardiomyopathy, coronary artery disease, hypertension, arrhythmia, hyperlipidemia, and insomnia. She is skilled in experimental cardiovascular physiology, molecular biology, signaling pathway analysis, preclinical animal models, translational interventions, and clinical guideline development. She has made significant scholarly contributions: she has authored 15 documents, received 154 Citations, and holds an h-index of 7, reflecting a growing impact. Among her honors and awards, she has been selected for the Guangdong Provincial Health Commission’s “Guangdong Special Support Program” and the “Youth Talent Support Program,” and she holds recognition as a young academic leader at her university; she also serves on multiple national and international professional committees and has contributed to guideline development, patent filing (2 invention patents), software intellectual property (1 software copyright), and the authorship of 9 books. Through mentorship she has guided student teams to high distinction in innovation competitions and has been invited as a keynote speaker at major conferences like the ESC Heart Failure Congress and the International Heart Congress. Given her solid educational foundation, extensive clinical and research experience, integrative medicine focus, leadership roles, and peer-recognized contributions, Prof. Dr. Tianhui Yuan is exceptionally well positioned to advance her field further, strengthen international collaborations, expand high-impact publication outputs, and mentor the next generation of integrative cardiovascular researchers.

Profile: Scopus

Featured Publications

  1. Ma, X., … Yuan, T. (2023). Regulation of phospholipid peroxidation signaling by a traditional Chinese medicine formula to prevent myocardial ischemia. Journal Name.

  2. Dong, X., Han, X., Zhang, X., … Yuan, T. (2022). A simplified herbal formula improves cardiac function and reduces inflammation in mice through the TLR-mediated NF-κB signaling pathway. Journal Name.

  3. Yang, Z., Xian, S., Yuan, T. (2020). Dexmedetomidine-mediated regulation of miR-17-3p in H9C2 cells after hypoxia/reoxygenation injury. Journal Name.

  4. Yuan, T., Chen, Y., Zhou, X., … (2019). Effectiveness and safety of Danshen injection on heart failure: protocol for a systematic review and meta-analysis. Journal Name.

  5. Wang, L., Gao, M., Chen, J., … (2015). Resveratrol ameliorates pressure overload-induced cardiac dysfunction and attenuates autophagy in rats. Journal Name.