Assoc. Prof. Dr khosrow khalifeh, University of Zanjan, Iran
Assoc. Prof. Dr. Khosrow Khalifeh is a leading Iranian biophysicist whose academic journey and research excellence have significantly advanced the fields of protein folding, bioinformatics, and molecular biophysics. Currently serving at the University of Zanjan, he specializes in investigating the structural dynamics of biomolecules and their functional interactions using experimental and computational approaches. His multidisciplinary teaching spans biophysical chemistry, radiation biology, and computational molecular biology. Dr. Khalifeh has authored several impactful publications in peer-reviewed journals and contributed chapters to prestigious Elsevier volumes. He is also known for pioneering work on luciferase proteins, chondroitinase enzymes, and the computational analysis of photoproteins. With over a decade of academic and research experience, his work not only enhances scientific understanding but also holds promise in areas like neurobiology and drug resistance. Dr. Khalifeh stands out as a deserving nominee for the Best Researcher Award due to his scholarly contributions, innovation, and commitment to education.
Publication Profile
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Education
Dr. Khosrow Khalifeh’s academic foundation is deeply rooted in the biological sciences and biophysics. He earned his Ph.D. in Biophysics from Tarbiat Modarres University, Tehran, in 2010. His doctoral research focused on the kinetic and thermodynamic behavior of wild-type and mutant Firefly Luciferase (Lampyris turkestanicus), exploring the complexities of protein folding and unfolding. He obtained his Master’s degree in Biophysics from the same institution in 2005, working on chemical modification of lysozyme and its impact on protein refolding kinetics. Prior to that, he completed his Bachelor of Science in Biology from Shahid Chamran University, Ahvaz, in 2000. His educational journey, characterized by strong theoretical and practical engagement with protein chemistry, molecular interactions, and biophysical mechanisms, has laid a solid groundwork for his later work in advanced biomolecular research and computational biology.
Experience
Dr. Khalifeh began his academic career as an Assistant Professor of Biophysics at the University of Zanjan in 2010. Over the next seven years, he actively contributed to teaching and research in molecular biophysics, eventually being promoted to Associate Professor in 2017. His teaching portfolio is extensive, including courses such as Biophysical Chemistry, Molecular Biophysics, Radiation Biophysics, Bioinformatics, and Biological Sequence Analysis. He also covers advanced topics like computational molecular biology and the philosophy of biology. Throughout his tenure, his teaching evaluations have consistently exceeded expectations, reflecting his commitment to academic excellence. His research integrates experimental biophysics and computational simulations, mentoring numerous graduate students while collaborating with national and international researchers. Dr. Khalifeh has built a reputation for combining innovative methodologies with solid pedagogical skills, and his ongoing efforts continue to shape the next generation of biophysicists in Iran and beyond.
Awards and Honors
Although specific awards and honors are not listed in the provided data, Assoc. Prof. Dr. Khosrow Khalifeh’s distinguished academic trajectory and peer recognition can be inferred from his consistently high teaching evaluations, publication record, and contributions to edited volumes by Academic Press (Elsevier). His selection as a co-author for high-impact book chapters such as “Spectroscopic Methods to Study Protein Folding Kinetics” and “Chondroitinase ABC I in Spinal Cord Injury” speaks volumes about his expertise and scientific standing. Dr. Khalifeh’s work has been published in reputable journals like International Journal of Biological Macromolecules, Spectrochimica Acta, Luminescence, European Biophysics Journal, and Scientific Reports. These accomplishments reflect peer recognition and academic influence, establishing him as a key thought leader in his field. His eligibility for the Best Researcher Award is further strengthened by this solid academic footprint and the originality of his contributions to biophysical research.
Research Focus
Dr. Khosrow Khalifeh’s research spans the intersecting domains of biophysics, bioinformatics, systems biology, and biotechnology. His primary focus lies in understanding protein folding and unfolding mechanisms, enzyme dynamics, and molecular interactions using both wet-lab experiments and in silico simulations. He has significantly contributed to the molecular study of photoproteins such as Mnemiopsin and enzymes like Chondroitinase ABC I and cyclomaltodextrinase. His research employs molecular dynamics simulations, structural modeling, and thermodynamic profiling to explore the functional consequences of site-directed mutations and ligand binding. Additionally, he has investigated protein-DNA interactions, protein engineering, and the biochemical effects of mutation-induced charge shifts, offering insights into disease-related protein dysfunctions and potential biotechnological applications. This cross-disciplinary focus positions Dr. Khalifeh at the cutting edge of biomolecular and computational biophysics, making his work highly impactful for both theoretical understanding and translational science.
Publication Top Notes
Interaction of lysozyme with gold nanorods: conformation and activity investigations
Roles of trehalose and magnesium sulfate on structural and functional stability of firefly luciferase
Thermodynamics of protein folding: methodology, data analysis and interpretation of data
Effect of arginine on pre-nucleus stage of interferon beta-1b aggregation
Critical role of a loop at C-terminal domain on the conformational stability and catalytic efficiency of chondroitinase ABC I
OCT4 spliced variants are highly expressed in brain cancer tissues and inhibition of OCT4B1 causes G2/M arrest in brain cancer cells
The role of trehalose for metastable state and functional form of recombinant interferon beta-1b