Rajendra Rohokale | Medicine and Health Sciences | Best Researcher Award
Dr Rajendra Rohokale, University of Florida, United States
Dr. Rajendra Rohokale is a Research Scientist at the University of Florida, specializing in Synthetic Organic Chemistry, Carbohydrate Chemistry, and Glycochemistry. With a Ph.D. from Savitribai Phule Pune University, his notable projects include synthesizing complex carbohydrates for therapeutic applications and developing fully synthetic cancer vaccines. Dr. Rohokale’s work has led to significant advancements in glycoimmunology and drug delivery. An experienced researcher and reviewer for prestigious journals, he has over 360 citations on Google Scholar and holds an Orchid ID: orcid.org/0000-0001-8083-0466. ๐๐งช๐ฌ๐
Publication profile
Education
๐ From 2010 to 2017, Rajendra Rohokale pursued a Ph.D. in Organic Chemistry at the Department of Chemistry, Savitribai Phule Pune University, Pune, India, under the guidance of Prof. Dilip D. Dhavale (F.A.Sc, F.N.A.Sc.). Their thesis was titled “Chiron Approach Towards the Syntheses of Amino Acids, Piperidine, Azepane, Polyhydroxylated Pyrrolizidine Alkaloids and Activation of Diazo-Ketones Using Visible Light Photoredox Catalysis and Dye.” [Name] earned their Master of Science (Organic Chemistry) (First Class) from the same university in 2009 and completed their Bachelor of Science (Chemistry) (First Class with Distinction) from New Arts, Science, and Commerce College, Ahmednagar in 2007. ๐๐ฌ
Experience
๐งช Since August 2023, I’ve been a Research Scientist at the University of Florida, Gainesville. From January 2019 to August 2023, I was a Post-doctoral Research Associate at the same institution. My work focuses on synthesizing complex carbohydrates and their conjugates for therapeutic applications, including the development of glycosphingolipids (GSLs) and monophosphoryl lipid-A derivatives as cancer vaccine carriers. I specialize in synthetic organic and carbohydrate chemistry, creating efficient methods for synthesizing oligosaccharides and glycoconjugates. My research aims to advance cancer immunotherapy and glycoimmunology, with significant contributions to medical science. ๐๐งซ๐ฌ
Presentations
He have actively participated in numerous esteemed conferences, including the Florida Heterocyclic Conference 2022 (FloHet 2022) at the University of Florida in March 2022 and the ChemPhotoChem-EJOC joint virtual symposium on Photoreact Catalysis in December 2021. He also attended FloHet 2020 at the University of Florida in March 2020. He presented a talk at the National Conference on “Bioinspired Materials in Science” at New Arts College, Pune, India, in January 2018. Additionally, He participated in the Satellite Meeting on Frontiers in the Chemistry & Biology of Oligosaccharides in January 2014 and attended various other international conferences from 2009 to 2013. ๐๐ฌ๐๐
Research focus
Dr. Rajendra Rohokale’s research focuses on the synthesis and functional analysis of glycosphingolipids (GSLs) and their interactions in cell membranes. His work spans developing bifunctional GSL probes for studying GSL-interacting proteins, creating novel vaccine adjuvants, and exploring bacterial polysaccharide-based antibacterial conjugate vaccines. He also delves into advanced chemical synthesis techniques for GSLs and their derivatives, utilizing methods like diastereoselective cycloaddition and chemoenzymatic synthesis. Dr. Rohokale’s contributions significantly impact medicinal chemistry, organic chemistry, and infectious disease research. ๐งช๐ฌ๐
Publication top notes
Bifunctional glycosphingolipid (GSL) probes to investigate GSL-interacting proteins in cell membranes
Diastereoselective 1,3-Dipolar Intramolecular Nitrone Olefin Cycloaddition (INOC) Reaction of a Sugar-derived Allyl Alcohol: Synthesis of Functionalized Aminocyclopentitols.
Monophosphoryl Lipid A-Rhamnose Conjugates as a New Class of Vaccine Adjuvants
Development in the Concept of Bacterial Polysaccharide Repeating Unit-Based Antibacterial Conjugate Vaccines
Structural characterization and analysis of different epimers of neutral glycosphingolipid LcGg4 by ion mobility spectrometry-mass spectrometry
A Diversity-Oriented Strategy for Chemical Synthesis of Glycosphingolipids: Synthesis of Glycosphingolipid LcGg4 and Its Analogues and Derivatives
Iridium(III)-Catalyzed Alkynylation of 2-(Hetero)arylquinazolin-4-one Scaffolds via CโH Bond Activation
Eosin y photoredox catalyzed net redox neutral reaction for regiospecific annulation to 3-sulfonylindoles: Via anion oxidation of sodium sulfinate salts
Metal-Free Synthesis of 3-Thiocyanatobenzothiophenes by Eosin Y Photoredox-Catalyzed Cascade Radical Annulation of 2-Alkynylthioanisoles
Visible-Light-Mediated Eosin Y Photoredox-Catalyzed Vicinal Thioamination of Alkynes: Radical Cascade Annulation Strategy for 2-Substituted-3-sulfenylindoles