Shiji Fang | Medicine | Best Researcher Award

Published on by Research Hypothesis

Best Researcher Award

Shiji Fang
Lishui Central Hospital, China

Shiji Fang
Affiliation Lishui Central Hospital
Country China
Scopus ID 57192204982
Documents 91
Citations 2,574
h-index 27
Subject Area Medicine
Event International Research Hypothesis Excellence Award
ORCID 0009-0004-4998-5039

Shiji Fang is a medical researcher affiliated with Lishui Central Hospital in China whose indexed research profile reflects sustained scholarly activity in biomedical and translational medicine. The available Scopus-derived profile records 91 documents, 2,574 citations and an h-index of 27, indicating a substantial body of indexed research and citation activity. [1][2]

Abstract

Shiji Fang’s research profile is situated within medicine and includes a substantial body of indexed scholarly work. The supplied publication record highlights research at the intersection of cancer biology, tumor microenvironment, immunotherapy and nanomedicine. Recent studies address mechanisms and therapeutic approaches involving immunogenic cell death, reactive oxygen species, endoplasmic reticulum stress, cellular senescence, copper homeostasis, ferroptosis, cuproptosis, chemoembolization and MRI-guided therapeutic systems. [1] [2]

Keywords

Shiji Fang; Best Researcher Award; Medicine; cancer research; hepatocellular carcinoma; immunotherapy; nanomedicine; immunogenic cell death; ferroptosis; cuproptosis; tumor biology; therapeutic delivery; translational medicine; oxidative stress; endoplasmic reticulum stress.

Introduction

Contemporary cancer research increasingly integrates molecular oncology with materials science, immunology and targeted therapeutic delivery. Hepatocellular carcinoma in particular presents a complex therapeutic environment in which tumor heterogeneity, immune suppression and resistance mechanisms can limit treatment effectiveness. Research that investigates interactions among tumor cells, immune pathways and therapeutic nanoplatforms therefore forms an important component of translational biomedical investigation.[2] [3]

Research Profile

The supplied Scopus profile identifies Shiji Fang with Author ID 57192204982 and lists Lishui Central Hospital, China, as the institutional affiliation. The profile is associated with the subject area of Medicine and records 91 indexed documents, 2,574 citations and an h-index of 27. [1]

Research characteristics

  • Primary discipline: Medicine.
  • Institutional affiliation: Lishui Central Hospital, China.
  • Scopus Author ID: 57192204982.
  • Indexed documents: 91.
  • Reported citations: 2,574.
  • Reported h-index: 27.
  • Major themes represented: cancer biology, hepatocellular carcinoma, immunotherapy, nanomedicine and regulated cell-death mechanisms.

Research Contributions

The supplied publications indicate several connected areas of research contribution. One strand examines how natural or bioactive compounds can influence cancer-cell death and stress-response pathways. The 2025 article on astragalin investigates immunogenic cell death in liver cancer in connection with NQO2, reactive oxygen species and endoplasmic reticulum stress. [2]

A second strand concerns the integration of cellular senescence with immune activation. The study published in Advanced Science describes a biomimetic nanomedicine approach designed around senescence-modulated immune activation and its potential relationship with immunotherapy efficacy in hepatocellular carcinoma. [3]

Publications

The following selected publications are taken from the supplied Scopus-derived research information. The list emphasizes recent 2025 articles and includes DOI identifiers where provided.

  1. Astragalin induces immunogenic cell death in liver cancer by targeting NQO2 to promote ROS-mediated endoplasmic reticulum stress pathway. Free Radical Biology and Medicine.
  2. Biomimetic Nanomedicine for Senescence-Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma. Advanced Science.
  3. Cascade-targeting copper homeostasis nano-regulators for mild-photothermal boosted cuproptosis/ferroptosis mediated breast cancer therapy. Journal of Nanobiotechnology.
  4. Corrigendum to “Fangchinoline inhibits metastasis and reduces inflammation-induced epithelial-mesenchymal transition by targeting the FOXM1-ADAM17 axis in hepatocellular carcinoma”. Cellular Signalling.

Research Impact

The supplied bibliometric indicators provide a quantitative view of the visibility of the research record. With 2,574 reported citations and an h-index of 27 across 91 indexed documents, the profile demonstrates sustained citation activity within the indexed scholarly literature. [1] Bibliometric measures should nevertheless be interpreted alongside publication quality, methodological rigor, authorship contributions and the substantive influence of individual studies.

Award Suitability

The Best Researcher Award within the International Research Hypothesis Excellence Award framework can be assessed using evidence concerning research productivity, scholarly visibility, thematic contribution and relevance to the broader research community. The supplied profile provides several measurable indicators, including 91 indexed documents, 2,574 citations and an h-index of 27. [1]

Conclusion

Shiji Fang’s supplied academic profile presents an established research record in Medicine, with affiliation to Lishui Central Hospital in China and a Scopus Author ID of 57192204982. The reported 91 documents, 2,574 citations and h-index of 27 provide quantitative indicators of scholarly activity and citation visibility. [1]

References

  1. Elsevier. (n.d.). Scopus author details: Shiji Fang, Author ID 57192204982. Scopus.
    https://www.scopus.com/pages/authors/57192204982
  2. Zheng, L., Zhao, Z., Chen, L., Yang, W., Ercolani, G., Qin, P., Lin, B., Han, M., Weng, Q., Zhang, Y., et al. (2025). Astragalin induces immunogenic cell death in liver cancer by targeting NQO2 to promote ROS-mediated endoplasmic reticulum stress pathway. Free Radical Biology and Medicine.
    https://doi.org/10.1016/j.freeradbiomed.2025.07.047
  3. Fang, S., Zheng, L., Lin, B., Chen, J., Hou, D., Ding, Y., Han, M., Qin, P., Wang, M., Guo, X., et al. (2025). Biomimetic Nanomedicine for Senescence-Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma. Advanced Science.
    https://doi.org/10.1002/advs.202517792
  4. Liang, X., Fang, S., Xin, Y., Lei, J., Wang, W., Wei, Y., Li, W., Li, C., Tang, H., Wei, X., et al. (2025). Cascade-targeting copper homeostasis nano-regulators for mild-photothermal boosted cuproptosis/ferroptosis mediated breast cancer therapy. Journal of Nanobiotechnology.
    https://doi.org/10.1186/s12951-025-03722-2
  5. Chen, M., Chen, Y., Chen, W., Chen, X., Guo, X., Yu, J., Guo, X., Wang, M., Zhang, X., Hu, Q., et al. (2025). Immune-activated microspheres for enhanced chemoembolization of hepatocellular carcinoma by blocking the adenosine A2A receptor. Acta Biomaterialia.
    https://doi.org/10.1016/j.actbio.2025.04.042
  6. Chen, X., Zhang, F., Lu, C., Wu, R., Yang, et al. (2025). Lactate-Fueled Theranostic Nanoplatforms for Enhanced MRI-Guided Ferroptosis Synergistic with Immunotherapy of Hepatocellular Carcinoma. ACS Applied Materials and Interfaces.
    https://doi.org/10.1021/acsami.4c21890

Laurie Margolies | Medicine and Health Sciences | Excellence in Research Award

Published on by Research Hypothesis

Dr. Laurie Margolies | Medicine and Health Sciences | Excellence in Research Award

Dr. Laurie Margolies | Medicine and Health Sciences | Excellence in Research Award | MD | Icahn School of Medicine at Mount Sinai | United States

Dr. Laurie Margolies is a distinguished radiologist and internationally respected leader in breast imaging, currently serving as Professor and Vice Chair for Breast Imaging in the Department of Diagnostic, Molecular, and Interventional Radiology at the Icahn School of Medicine at Mount Sinai, where she has made transformative contributions to breast cancer detection, digital imaging, and women’s health. Dr. Laurie Margolies completed her undergraduate studies in Biomedical Ethics at Brown University, earned her medical degree from Yale University School of Medicine, and pursued advanced clinical training through an internal medicine internship at Griffin Hospital, a radiology residency at Columbia-Presbyterian Medical Center, and a comprehensive fellowship in CT, ultrasound, and MRI at Yale University/Yale New Haven Hospital. Her professional experience spans decades of academic appointments, including Instructor at Yale, rising through faculty ranks at Mount Sinai from Assistant Professor to full Professor, while simultaneously serving as System Chief of Breast Imaging across multiple hospitals, Director of Breast Imaging at Mount Sinai Hospital, and Chief of Breast Imaging at the Dubin Breast Center. Dr. Laurie Margolies’s research interests center on breast cancer screening optimization, digital mammography, cardiovascular risk evaluation through mammographic arterial calcifications, health disparity reduction, culturally targeted education programs, imaging physics, AI-driven diagnostic tools, and cross-disciplinary cancer detection methods. Her research skills include expertise in multimodality breast imaging, tomosynthesis assessment, radiologic quality control, population-based screening program development, clinical guideline evaluation, and participation in collaborative research teams across oncology, epidemiology, psychology, and medical physics. She has contributed to impactful studies published in reputable journals such as the Journal of Breast Imaging, Clinical Imaging, Journal of Cancer Education, and PEC Innovation, and she has served on multiple advisory boards for leading medical technology companies, advancing AI-assisted imaging development. Dr. Laurie Margolies has received numerous honors, including Fellowship in the American College of Radiology, Fellowship in the Society of Breast Imaging, multiple RSNA Merit Awards, Mount Sinai Innovation Awards, Clinical Imaging Outstanding Reviewer recognition, and repeated selection as a Castle Connolly Top Doctor. She has served on key institutional committees, leadership panels, and mentoring programs, significantly shaping radiologic quality improvement and cancer screening strategies. Dr. Laurie Margolies continues to influence clinical practice through her dedication to research, patient-centered care, and educational advancement, embodying excellence in academic radiology and demonstrating ongoing potential to elevate global breast imaging standards.

Profile: ORCID | Google Scholar

Featured Publications 

  1. Margolies, L. R., Spear, G. G., Payne, J. I., Iles, S. E., & Abdolell, M. (2025). Artificial intelligence for assessment of digital mammography positioning reveals persistent challenges.

  2. Rossi, J., Cho, L., Newell, M. S., Venta, L. A., Montgomery, G. H., Destounis, S. V., Brem, R. F., Parghi, C., & Margolies, L. R. (2025). Breast arterial calcifications on mammography: A review of the literature.

  3. Mullen, L. A., Ambinder, E. B., Talati, N., & Margolies, L. R. (2023). Mammography information systems: A survey of breast imaging radiologist satisfaction and perspectives.

  4. Head, K. J., Harrington, N. G., Schnur, J. B., Margolies, L., & Montgomery, G. H. (2022). Examining gain- and loss-framed messages in a novel breast cancer screening/cardiovascular context: Does framing matter.

  5. Vang, S., Margolies, L. R., & Jandorf, L. (2022). Screening mammogram adherence in medically underserved women: Does language preference matter.

  6. Fung, J., Vang, S., Margolies, L. R., Li, A., Blondeau-Lecomte, E., Li, A., & Jandorf, L. (2021). Developing a culturally and linguistically targeted breast cancer educational program for a multicultural population.

  7. Margolies, L. R., Salvatore, M., Yip, R., Tam, K., Bertolini, A., Henschke, C., & Yankelevitz, D. (2018). The chest radiologist’s role in invasive breast cancer detection.