Xuemin Jin | Medical Hypotheses | Best Researcher Award

Assoc. Prof. Dr Xuemin Jin, Jilin University, China

Assoc. Prof. Dr. Xuemin Jin is a leading scientist in the field of veterinary parasitology and zoonotic diseases. With over a decade of research experience, she has contributed significantly to understanding host–parasite–microbiome interactions, helminth immunology, and vaccine development. Currently an Associate Professor at the Institute of Zoonoses, Jilin University, she holds key roles in national and international scientific bodies, such as the International Commission on Trichinosis and the OIE Collaborating Centre for Foodborne Parasitic Diseases. Her work bridges parasitology, microbiota, and immunology, with her findings published in high-impact journals like Signal Transduction and Targeted Therapy, Gut Microbes, and PLoS Pathogens. A recipient of several prestigious grants from China’s National Natural Science Foundation and the Ministry of Science and Technology, Dr. Jin is a recognized leader advancing the frontiers of zoonotic parasitic disease research.

Publication Profile

Orcid

Education

Dr. Xuemin Jin completed her academic training entirely at Jilin University, one of China’s top veterinary and medical research institutions. She earned her Bachelor of Science (B.S.) in Veterinary Medicine from the College of Veterinary Medicine in 2015. She then pursued a Ph.D. in Veterinary Parasitology, completed in 2020, where she explored the molecular and immunological mechanisms of Trichinella spiralis. Following her doctorate, she continued her scholarly path as a Postdoctoral Fellow from 2020 to 2022 at the Institute of Zoonoses, Jilin University, where she specialized in zoonotic parasitic infections and host-pathogen interactions. Her academic trajectory showcases a strong foundation in experimental parasitology, immunomodulation, and zoonotic disease control strategies.

Experience

Dr. Jin began her academic career as a Lecturer at the College of Veterinary Medicine, Jilin University (2020–2022), contributing to teaching and mentoring in parasitology and immunopathology. Since 2022, she has been serving as an Associate Professor at the Institute of Zoonoses, where she leads research on Trichinella spiralis and intestinal helminth-microbiota interactions. She plays a key role in collaborative vaccine development initiatives and oversees multiple research grants. Additionally, she has held notable academic positions including committee memberships in the 8th Veterinary Discipline Evaluation Group of the State Council, OIE Collaborating Centre, and the International Commission on Trichinosis. These roles highlight her credibility and thought leadership in the field.

Awards and Honors

Dr. Jin has received multiple accolades through prestigious national-level funding, including leading and sub-leading roles in National Natural Science Foundation of China’s Key Program and 14th Five-Year Plan Key R&D Projects by the Ministry of Science and Technology. These grants, totaling millions of RMB, underscore the scientific community’s trust in her expertise. She serves as a Committee Member for global parasitology initiatives such as the International Commission on Trichinosis, and holds national recognition through the Veterinary Discipline Evaluation Group of the Academic Degrees Committee of the State Council. Her continuous engagement in international and policy-level scientific networks highlights her influential status in zoonotic and veterinary research.

Research Focus

Dr. Jin’s primary research centers on zoonotic parasitic diseases, particularly Trichinella spiralis, integrating host immunity, microbiome regulation, and vaccine development. Her work reveals novel immunological mechanisms, such as the role of β-glucans and intestinal bacteria (e.g., Akkermansia muciniphila) in modulating helminth-induced pathology and immune responses. She has made groundbreaking findings in TLR2/NLRP3-mediated pathways, host-protective immunity, and the cross-talk between helminths and commensal gut bacteria. Additionally, she contributes to the development of recombinant and genetically engineered vaccines for zoonotic infections, aligning with global One Health strategies. Her research is interdisciplinary, with applications in veterinary public health, immunology, and parasitic disease control.

Publication Top Notes

The effect of β-Glucan induced intestinal trained immunity against Trichinella spiralis infection.

Trichinella spiralis alleviates LPS-induced acute lung injury by modulating the protective Th2 immune response.

Helminth alleviates COVID-19-related cytokine storm in an IL-9-dependent way.

Yeast β-glucan promotes antiviral type I interferon response via dectin-1.

Trichinella spiralis excretory/secretory products from adult worms inhibit NETosis and regulate the production of cytokines from neutrophils.

Akkermansia muciniphila participates in the host protection against helminth-induced cardiac fibrosis via TLR2.

In vitro knockdown of TsDNase II-7 suppresses Trichinella spiralis invasion into the host’s intestinal epithelial cells.

Hristo Gagov | Hypothesis Fundamentals | Best Researcher Award

Prof Hristo Gagov, Sofia University ‘St. Kliment Ohridski’, Bulgaria

Prof. Hristo Gagov is a distinguished physiologist specializing in Animal and Human Physiology, Pharmacology, and Toxicology 🧬. He earned his MD in Molecular and Functional Biology from Sofia University (1988) 🎓 and a PhD from the Institute of Physiology, Bulgarian Academy of Sciences 🏅. As Head of the “Excitable Cells” Laboratory, his research spans cardiovascular health, ion channels, intracellular signaling, and nanotechnology ⚛️. With 82 publications 📑 and 510 citations, he is a key member of the Bulgarian Physiological Society. His international collaborations include work in Germany and Italy 🇩🇪🇮🇹.

Education

Prof. Hristo Gagov 🎓 earned his MD in Molecular and Functional Biology from Sofia University ‘St. Kliment Ohridski’ in 1988 🏛️. With a passion for physiology and biological sciences 🧬, he pursued a PhD at the Institute of Physiology, Bulgarian Academy of Sciences 🔬. His research contributions span molecular biology, physiological processes, and functional analysis of biological systems 🏥🔍. Through years of dedication to academia and scientific discovery 📚, Prof. Gagov has played a crucial role in advancing knowledge in his field, mentoring future researchers, and contributing to groundbreaking studies in molecular and functional biology 🌍🔎.

Experience

Prof. Hristo Gagov is a distinguished researcher with an impressive academic footprint 📚🔬. He has authored over 82 scientific publications, showcasing his dedication to advancing knowledge. Among these, 68 are indexed with an impact factor, highlighting the high quality and recognition of his work 📑⭐. His research excellence is further reflected in his Scopus H-index of 14, demonstrating the significant influence of his studies in the scientific community 📊🏆. Through rigorous research and impactful contributions, Prof. Gagov continues to shape his field, leaving a lasting mark on global academia 🌍🔎.

Diverse Research Areas

Prof. Hristo Gagov is a distinguished researcher whose expertise bridges multiple disciplines, including cardiovascular physiology ❤️, ion channels 🔬, intracellular signaling ⚡, aging ⏳, nanotechnology 🧪, and electrophysiology 🧠. His interdisciplinary approach has led to significant advancements in understanding cellular mechanisms and their implications for health and disease. With a keen focus on innovation, he explores how nanotechnology can enhance biomedical applications and how ion channels influence physiological functions. His work contributes to the broader scientific community, paving the way for novel therapeutic strategies and deeper insights into aging and cardiovascular health. 🌍📚

Award-Winning

Prof. Hristo Gagov is a distinguished researcher known for his outstanding contributions to scientific projects 🔬📚. His innovative work has earned him prestigious research awards 🏆🎖️, recognizing his dedication and impact in his field. With a commitment to advancing knowledge and fostering scientific excellence, he has played a crucial role in groundbreaking research initiatives 🌍🔍. His achievements highlight his expertise and dedication to pushing the boundaries of discovery 🚀📖. Through his remarkable efforts, Prof. Gagov continues to inspire the academic community, contributing valuable insights and advancements that shape the future of research and innovation 🧠💡.

Research Focus

Prof. Hristo Gagov’s research focuses on molecular physiology, endocrinology, and vascular biology 🧬🩺. His studies explore redox balance in endocrine-related metabolic diseases and cancer 🦠⚖️, emphasizing reductive stress and its pathological effects. He investigates Sirtuin 1’s role in aging and hormonal regulation ⏳🔬, along with the mechanisms of vascular smooth muscle function 💓🩸, particularly in hypertension. Additionally, he examines anticarcinogenic agents like EF24, analyzing their pharmacokinetics, efficacy, and nanoformulation for drug delivery 💊🚀. His interdisciplinary work bridges molecular medicine, aging, and cardiovascular health, contributing to therapeutic advancements 🏥📈.