Juhui Qiu | Biology and Life Sciences | Excellence in Innovation Award
Prof. Dr Juhui Qiu, Chongqing University, China
Prof. Dr. Juhui Qiu is a distinguished researcher in cardiovascular biomechanics, focusing on endothelial cell biology, hematopoietic stem cell fate, and shear stress-induced atherosclerosis. With expertise in zebrafish and mouse models, his groundbreaking research unravels the cellular and molecular mechanisms driving cardiovascular diseases. As a leading scientist, he has secured multiple national research grants and has over a decade of experience in academia and biomedical engineering. His contributions to vascular implant development and mechanobiology have earned him prestigious awards, including the Chongqing Science and Technology Progress Award. With a dynamic research team and international collaborations, Prof. Qiu continues to push the frontiers of vascular biology and regenerative medicine. His work not only advances fundamental science but also offers potential therapeutic insights for blood disorders and cardiovascular health.
Publication Profile
Education
Prof. Dr. Juhui Qiu π holds a Ph.D. in Biomedical Engineering from Tsinghua University, China (2011) π¬, an M.Sc. in Biomedical Engineering from Chongqing University (2008) πβοΈ, and a B.Sc. in Biotechnology from Chongqing University (2005) ποΈπ§ͺ. His academic journey began with a strong foundation in biotechnology, later advancing into biomedical engineering to specialize in vascular biology and mechanobiology. During his Ph.D. at Tsinghua University, he conducted pioneering research on hemodynamic forces in endothelial cell function, laying the groundwork for his current studies on atherosclerosis and hematopoietic stem cell migration. His interdisciplinary expertise in cell biology, molecular mechanics, and bioengineering has enabled him to make significant contributions to cardiovascular research. As a postdoctoral fellow, he further explored endothelial mechanotransduction, deepening his impact in regenerative medicine and vascular therapeutics. His work continues to bridge fundamental research and clinical applications, driving innovations in cardiovascular disease treatment. π§¬π«π¬
Experience
Prof. Dr. Juhui Qiu is a distinguished researcher specializing in endothelial mechanobiology and cardiovascular disease. Since 2018, he has served as a professor at Chongqing University ποΈπ¨βπ«, leading groundbreaking studies on vascular implants, atherosclerosis, and endothelial cell behavior under shear stress. As Deputy Director of the National Local Joint Engineering Laboratory for Vascular Implant Development (2020β2025) π₯βοΈ, he oversees innovative vascular interventions. His postdoctoral research at Tsinghua University (2011β2013) ππ§ͺ focused on endothelial shear stress response and hematopoiesis. From 2016 to 2022, he engaged in international research collaborations ππ¬, contributing to biomechanical modeling and cardiovascular disease studies. A dedicated mentor ππ§βπ«, he supervises 14 students, including Ph.D. candidates and international researchers. His expertise in combining experimental and computational approaches has led to significant advancements in cardiovascular research, positioning him as a leader in vascular biology and medical innovation. ππ
Awards and Honors
Prof. Dr. Juhui Qiu has received numerous prestigious awards for his groundbreaking contributions to cardiovascular biomechanics and vascular research. In 2020, he was honored with the First Prize of the Chongqing Science & Technology Progress Award π for his pioneering work in vascular implants and anti-thrombosis interventions. His research on hemodynamic regulation of TET1s in atherosclerosis earned him the Excellent Academic Paper Award π€ at the 12th National Biomechanics Conference in 2018. In 2017, he received the First Prize of the Chongqing University Natural Science Award π for his mechanobiological insights into atherosclerotic plaque rupture. His exceptional postdoctoral research on endothelial mechanobiology was recognized with the Tsinghua-Peking Joint Center for Life Sciences Postdoctoral Excellence Award ποΈ in 2013. Additionally, he was awarded the Tsinghua University Postdoctoral Support Program π in 2012 and named a Chongqing Excellent Graduate Student π in 2011. These honors reflect his profound impact on vascular biology and regenerative medicine. π©Έπ©Ίπ¬
Research Focus
Prof. Qiuβs research focuses on cardiovascular biomechanics, particularly the impact of hemodynamic shear stress on endothelial cell fate and atherosclerosis. His studies, using zebrafish and mouse models, explore oscillatory shear stress-induced atherosclerosis π«π’, the emergence of hematopoietic stem cells from endothelial cells π§¬π©Έ, endothelial mechanotransduction and inflammatory responses ππ₯, and the molecular pathways governing vascular development and homeostasis π§ͺπ. By integrating cell biology, molecular biology, and biomechanics, his team aims to uncover critical mechanisms in vascular disease and regenerative medicine. With numerous high-impact publications and funded research projects, his work bridges fundamental science with potential therapeutic applications, advancing our understanding of cardiovascular health and disease. ππ
Publication Top Notes
1οΈβ£ An animal model recapitulates human hepatic diseases associated with GATA6 mutations. Proc Natl Acad Sci U S A, 2025
2οΈβ£ The interplay between histone modifications and nuclear lamina in genome regulation. J Genet Genomics, 2025
3οΈβ£ Genetically encoded FRET biosensor for live-cell visualization of Lamin A phosphorylation. Biomater Res, 2024
4οΈβ£ Single-cell and bulk RNA-seq reveals endothelial engulfment in atherosclerosis. Genes Dis, 2024
5οΈβ£ Oscillatory shear stress-induced downregulation of TET1s affects endothelial cell polarity. APL Bioeng, 2023
6οΈβ£ Mechano-sensitive TET1s inhibits endothelial athero-susceptible phenotype via YAP regulation. Genes Dis, 2023
7οΈβ£ Unraveling the antioxidant behavior of self-assembly Ξ²-Sheet in silk fibroin. Redox Biol, 2024
8οΈβ£ Silk fibroin promotes H3K9me3 expression and chromatin reorganization in endothelial cells. APL Bioeng, 2024